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Ephedra: Is It Worth the Risk?
by Denise Feeley, MS, RD, CDE May/June 2003 For the Washington Running Report
Nutrition Advice
In February of this year, 23-year-old Baltimore Orioles pitcher
Steve Bechler collapsed during practice and died later in the
day. His autopsy revealed that it was likely his death was
triggered by the use of the herbal supplement ephedra. This
triggered a media frenzy and at the end of February the Food &
Drug Administration announced that it will investigate whether
dietary supplements that contain ephedra pose "significant or
unreasonable risks" to users. Supplements that contain the herb
are now required to display a warning label stating that use
may "increase the risk for heart attack, seizures, stroke, or
death." Ephedra has been linked to more than one hundred deaths
in college and high school athletes and the FDA believes that
ephedra accounts for approximately sixty-four percent of the
reported adverse events associated with supplement use. Ephedra, or Ma Huang, is an herb that is grown in the Far East
and has been used for centuries to treat respiratory ailments
such as asthma. Ephedrine or pseudoephedrine is the manmade
derivative of ephedra that is found in over the counter
medications (Sudafed) and is used to treat respiratory and sinus
congestion. Ephedra is a powerful central nervous system
stimulant that increases the release of the catecholamine
epinephrine, which causes vasoconstriction, increased heart rate
and blood pressure, and subsequently increases the metabolic
rate. The short-term side effects include increased energy
levels, nervousness, jitteriness, and headaches. These side
effects can also contribute to a depression in appetite and,
combined with the increase in metabolic rate, weight loss may
ensue. Caffeine, which is also a stimulant, has been added to
many of the supplements containing ephedra, which exacerbates
the stimulatory effects as well as the side effects. Due to these effects, ephedra (with or without caffeine) has
been primarily marketed as a weight loss agent but has also been
marketed to athletes as a performance enhancer. Numerous studies
have been done evaluating the effects of the herb on weight
loss. Most of these studies are not deemed "scientific" mainly
due to either too few subjects in the studies or the studies
were not long enough to demonstrate practical results. Some of
these studies did show a modest short-term (over two months)
weight loss in combination with diet and exercise. Some studies
have also shown a modest short-term effect on performance; the
effects on long term performance have not been studied and are
therefore unknown at this time. There is no doubt that the herb increases energy levels and may
cause some weight loss, especially when combined with caffeine.
However, the short-term benefits need to be weighed against the
negative effects of the herb. The consequences of losing a few
pounds or shaving a few seconds off of your 10K may be long-term
and may not be worth it. Denise Feeley is an avid runner and Registered Dietitian with
more than eight years of experience counseling athletes. She is
currently an adjunct professor in the Department of Exercise
Science at George Washington University. She is available for
nutrition counseling. For information or questions contact her
at denf44@yahoo.com.
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